Apple phenolic extracts ameliorate lead-induced cognitive impairment and depression- and anxiety-like behavior in mice by abating oxidative stress, inflammation and apoptosis<i>via</i>the miR-22-3p/SIRT1 axis
Yong-Feng Ren, Dongxiao Sun‐Waterhouse, Fangxin Ouyang, Xintong Tan, Dapeng Li, Longhua Xu, Bo Li, Yongli Wang, Feng Li
Abstract
antioxidant, anti-inflammatory and anti-apoptotic actions.
Topics & Concepts
Oxidative stressNeurotoxicityChemistryPharmacologyApoptosisEndocrinologyNeuroinflammationMalondialdehydeElevated plus mazeInternal medicineInflammationMedicineBiochemistryToxicityAnxietyOrganic chemistryPsychiatryMedicinal Plants and NeuroprotectionHeavy Metal Exposure and ToxicityNoise Effects and Management