Lipopolysaccharide influences the plasma and brain pharmacokinetics of subcutaneously-administered HsTX1[R14A], a KV1.3-blocking peptide
Sanjeevini Babu Reddiar, Liang Jin, Dorothy C.C. Wai, Agota Csóti, György Panyi, Raymond S. Norton, Joseph A. Nicolazzo
Topics & Concepts
NeuroinflammationLipopolysaccharideMicrogliaPharmacologyBlood–brain barrierDownregulation and upregulationChemistryPharmacokineticsEndocrinologyInternal medicineInflammationMedicineCentral nervous systemBiochemistryGeneNeuroinflammation and Neurodegeneration MechanismsS100 Proteins and AnnexinsAlzheimer's disease research and treatments