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Novel sampangine derivatives as potent inhibitors of Cu2+-mediated amyloid-β protein aggregation, oxidative stress and inflammation

Xiaoyan Zou, Ren-ren Xie, Wěi Li, Chun-ling Su, Yu-si Chen, Huang Tang

2021International Journal of Biological Macromolecules11 citationsDOI

Topics & Concepts

ChemistryIsothermal titration calorimetryProinflammatory cytokineOxidative stressChelationBlood–brain barrierCholinesteraseAcetylcholinesteraseMembrane permeabilityBiochemistryBiophysicsMembranePharmacologyInflammationEnzymeOrganic chemistryBiologyCentral nervous systemImmunologyNeuroscienceAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesMedicinal Plants and Neuroprotection
Novel sampangine derivatives as potent inhibitors of Cu2+-mediated amyloid-β protein aggregation, oxidative stress and inflammation | Litcius