Two-point Dixon and six-point Dixon magnetic resonance techniques in the detection, quantification and grading of hepatic steatosis
Mohamed Elfaal, Alanna Supersad, Craig Ferguson, Stephanie Locas, Florin Manolea, Mitchell P. Wilson, Medica Sam, Wendy Tu, Gavin Low
Abstract
BACKGROUND: Hepatic steatosis is a very common problem worldwide. AIM: To assess the performance of two- and six-point Dixon magnetic resonance (MR) techniques in the detection, quantification and grading of hepatic steatosis. METHODS: A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease. MR sequences included two-point Dixon, six-point Dixon, MR spectroscopy (MRS) and MR elastography. Fat fraction (FF) estimates on the Dixon techniques were compared to the MRS-proton density FF (PDFF). Statistical tests used included Pearson's correlation and receiver operating characteristic. RESULTS: < 0.01). CONCLUSION: Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions.