Efficacy of probiotics on cognition, and biomarkers of inflammation and oxidative stress in adults with Alzheimer’s disease or mild cognitive impairment — a meta-analysis of randomized controlled trials
Haoyue Den, Xunhu Dong, Mingliang Chen, Zhongmin Zou
Abstract
= 0.0%) post-intervention levels between the probiotics and control group. This meta-analysis indicated that probiotics improved cognitive performance in AD or MCI patients, possibly through decreasing levels of inflammatory and oxidative biomarkers. However, current evidence is insufficient, and more reliable evidence from large-scale, long-period, RCT is needed.
Topics & Concepts
Randomized controlled trialMeta-analysisMedicineCochrane LibraryInternal medicineCognitionDiseaseCognitive declineClinical trialPhysical therapyBioinformaticsDementiaPsychiatryBiologyGut microbiota and healthProbiotics and Fermented FoodsNutritional Studies and Diet