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Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1

M. Tanaka, Takeshi Yokoyama, Hironori Saito, Madoka Nishimoto, Kengo Tsuda, Naoyuki Sotta, Hideki Shigematsu, Mikako Shirouzu, Shintaro Iwasaki, Takuhiro Ito, Toru Fujiwara

2024Nature Chemical Biology10 citationsDOI

Topics & Concepts

Ribosome profilingTranslation (biology)Eukaryotic translationOpen reading frameRibosomeFive prime untranslated regionBiologyUpstream open reading frameBoric acidCell biologyStart codonChemistryBiochemistryGeneticsRNAMessenger RNAGenePeptide sequenceOrganic chemistryRNA and protein synthesis mechanismsRNA modifications and cancerRNA Research and Splicing
Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1 | Litcius