Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia, and psychiatric behavior in mice
Xiang Chen, Tong Chen, Chen Dong, Huiyao Chen, Xinran Dong, Lin Yang, Liyuan Hu, Huijun Wang, Bingbing Wu, Ye Yao, Yu Xiong, Man Xiong, Yifeng Lin, Wenhao Zhou
Topics & Concepts
CerebellumBiologyNeurosciencePurkinje cellNeurogenesisCerebellar ataxiaNeuronCerebellar hypoplasia (non-human)Cerebellar cortexAtaxiaFetal and Pediatric Neurological DisordersSingle-cell and spatial transcriptomicsPrenatal Screening and Diagnostics