Rifampicin‐induced acute tubulointerstitial nephritis during pulmonary tuberculosis treatment: A case report
C. Moussa, Samia Esbaa, Houda Rouis, Nada Sellami, M. Hajji, Yoldez Houcine, Amel Khattab, I. Khouaja, I. Zendah, Sonia Maâlej
Abstract
Drug-induced tubulointerstitial nephritis is an uncommon complication in patients on anti-tuberculosis therapy that can lead to permanent kidney damage. Rifampicin is the most offending drug. We report a case of a 41-years old man being treated for pulmonary tuberculosis and presenting with tubulointerstitial nephritis associated with rifampicin. We focus on diagnosis features and therapeutic challenges.
Topics & Concepts
MedicineRifampicinTuberculosisNephritisPulmonary tuberculosisComplicationDrugInternal medicineSurgeryIntensive care medicinePathologyPharmacologyNephrotoxicity and Medicinal PlantsDrug-Induced Hepatotoxicity and ProtectionRenal Diseases and Glomerulopathies