Multimechanism biological profiling of tetrahydro-β-carboline analogues as selective HDAC6 inhibitors for the treatment of Alzheimer's disease
Ting Liang, Shiru Liu, Baiyun Dang, Xiaofa Luan, Yifan Guo, Raphael R. Steimbach, Jiadong Hu, Long Lu, Peiyu Yue, Ruotian Wang, Meng Zheng, Jin‐Ming Gao, Xia Yin, Xin Chen
Topics & Concepts
ChemistryNeuroprotectionHDAC6ZebrafishIn vivoPharmacologyNeurotrophinCatalaseAlzheimer's diseaseOxidative stressBiochemistryHistone deacetylaseDiseaseBiologyMedicineInternal medicineHistoneReceptorGeneBiotechnologyHistone Deacetylase Inhibitors ResearchCholinesterase and Neurodegenerative DiseasesPeptidase Inhibition and Analysis