The role of STAT3/VAV3 in glucolipid metabolism during the development of HFD-induced MAFLD
Yue J, Pengcheng Luo, Yu Cao, Dewei Peng, Shengqi Huo, Junyi Guo, Moran Wang, Wei Shi, Cuntai Zhang, Sheng Li, Li Lin, Jiagao Lv
Abstract
. In conclusion, the STAT3/VAV3 signaling pathway might play a significant role in MAFLD by regulating glucose and cholesterol metabolism, and VAV3 might be a potential therapeutic strategy which could consequently ameliorate MAFLD.
Topics & Concepts
MetabolismChemistryInternal medicineEndocrinologyBiologyBiochemistryMedicineLiver Disease Diagnosis and TreatmentCardiovascular Function and Risk FactorsDiabetes and associated disorders