Broad Spectrum Antibiotic Xanthocillin X Effectively Kills <i>Acinetobacter baumannii</i> <i>via</i> Dysregulation of Heme Biosynthesis
Ines Hübner, Justin A. Shapiro, Jörn Hoßmann, Jonas Drechsel, Stephan M. Hacker, Philip N. Rather, Dietmar H. Pieper, William M. Wuest, Stephan A. Sieber
Abstract
represents a promising antibiotic displaying activity even against multidrug resistant strains, while exhibiting low toxicity to human cells.
Topics & Concepts
HemeAcinetobacter baumanniiEnzymeBiosynthesisBiologyBiochemistryCofactorBacteriaMicrobiologyChemistryPseudomonas aeruginosaGeneticsAntibiotic Resistance in BacteriaBiochemical and Molecular ResearchBacterial Genetics and Biotechnology