Targeting the YAP-TEAD interaction interface for therapeutic intervention in glioblastoma
Jacquelyn T. Saunders, Brent Holmes, Angelica Benavides-Serrato, Sunil Kumar, Robert N. Nishimura, Joseph Gera
Topics & Concepts
Hippo signaling pathwayCancer researchGlioblastomaDownregulation and upregulationBiologyYAP1Transcription factorEffectorFOXM1Cell biologyGeneticsGeneHippo pathway signaling and YAP/TAZCellular Mechanics and InteractionsFOXO transcription factor regulation