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MUC1 induces the accumulation of Foxp3+ Treg cells in the tumor microenvironment to promote the growth and metastasis of cholangiocarcinoma through the EGFR/PI3K/Akt signaling pathway

Guofeng Zhang, Zheng Ge, Haipeng Zhang, Ling Qiu

2023International Immunopharmacology35 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayCancer researchProtein kinase BCarcinogenesisTumor microenvironmentMUC1FOXP3Signal transductionBiologyMetastasisImmunologyCell biologyCancerAntigenImmune systemGeneticsTumor cellsCholangiocarcinoma and Gallbladder Cancer StudiesCancer-related molecular mechanisms researchRNA modifications and cancer
MUC1 induces the accumulation of Foxp3+ Treg cells in the tumor microenvironment to promote the growth and metastasis of cholangiocarcinoma through the EGFR/PI3K/Akt signaling pathway | Litcius