Environmental Free-Living Amoebae Can Predate on Diverse Antibiotic-Resistant Human Pathogens
Félix Bornier, Eline Zas, Damien Potheret, Maria-Halima Laaberki, Bénédicte Coupat-Goutaland, Xavier Charpentier
Abstract
experiments using model amoebae. Here, we sought to isolate environmental amoebae and to test their predation on diverse human pathogens, with results that challenge conclusions based on model amoebae. We found that the natural environment is a rich source of diverse amoebae with broad-spectrum predatory activities against human pathogens, including highly virulent and antibiotic-resistant clinical isolates.
Topics & Concepts
BiologyMicrobiologyHuman pathogenProtozoaAcanthamoebaAntibiotic resistanceBacteriaAntibioticsEcologyGeneticsLegionella and Acanthamoeba researchVibrio bacteria research studiesBacterial biofilms and quorum sensing