One step synthesis of unsymmetrical 1,3-disubstituted BCP ketones<i>via</i>nickel/photoredox-catalyzed [1.1.1]propellane multicomponent dicarbofunctionalization
Weichen Huang, Sebastian Keeß, Gary A. Molander
Abstract
K coupling partners, thus expanding the scope of this paradigm. Further transformation of disubstituted-BCP ketones into a variety of other BCP derivatives demonstrates the synthetic value of this developed method.
Topics & Concepts
ChemistryCombinatorial chemistryCatalysisArylNickelBioisostereChemical synthesisOrganic chemistryAlkylBiochemistryIn vitroRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques