First Case of COVID-19-Associated Collapsing Glomerulopathy in Sub-Saharan Africa
Yannick Mayamba Nlandu, J.R. Makulo, Nestor M Pakasa, Ernest Kiswaya Sumaili, Clarisse Nsenga Nkondi, Justine Busanga Bukabau, François Kabongo Beya, Nazaire Mangani Nseka, François Bompeka Lepira, Raoul Bergner
Abstract
Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there is growing evidence coming out of Africa of glomerular involvement, especially collapsing glomerulopathy seen particularly in people of African descent. We report a case of collapsing glomerulopathy revealed by acute kidney injury and a new onset of full blown nephrotic syndrome in a black Congolese patient coinfected with COVID-19 and malaria.