Chemotherapeutic drugs induce oxidative stress associated with DNA repair and metabolism modulation
Yujie Zhang, Chunyang Ding, Wenkang Zhu, Xinyu Li, Techang Chen, Qingxi Liu, Sa Zhou, Tongcun Zhang, Wenjian Ma
Topics & Concepts
DNA damageDNA repairOxidative stressGene knockdownProinflammatory cytokineReactive oxygen speciesDoxorubicinHomologous recombinationBiologyCisplatinCell biologyCancer researchMitochondrial ROSChemistryDNABiochemistryInflammationImmunologyGeneticsApoptosisChemotherapyDNA Repair MechanismsCancer therapeutics and mechanismsChemotherapy-induced organ toxicity mitigation