Structure of the M2 muscarinic receptor–β-arrestin complex in a lipid nanodisc
Dean P. Staus, Hongli Hu, Michael J. Robertson, A.L.W. Kleinhenz, Laura M. Wingler, W. Darrell Capel, Naomi R. Latorraca, Robert J. Lefkowitz, Georgios Skiniotis
Topics & Concepts
Heterotrimeric G proteinG protein-coupled receptorNanodiscG proteinArrestinCell biologyMuscarinic acetylcholine receptorBiophysicsLipid bilayerRhodopsinBiologyChemistryReceptorBiochemistrySignal transductionMembraneRetinalReceptor Mechanisms and SignalingLipid Membrane Structure and BehaviorMass Spectrometry Techniques and Applications