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Superoxide produced by mitochondrial complex III plays a pivotal role in the execution of ferroptosis induced by cysteine starvation

Takujiro Homma, Sho Kobayashi, Hideyo Sato, Junichi Fujii

2021Archives of Biochemistry and Biophysics51 citationsDOI

Topics & Concepts

SuperoxideProgrammed cell deathMitochondrionLipid peroxidationCell biologyIntracellularGPX4GlutathioneChemistryBiochemistryBiologyApoptosisOxidative stressSuperoxide dismutaseGlutathione peroxidaseEnzymeFerroptosis and cancer prognosisRNA modifications and cancerEpigenetics and DNA Methylation
Superoxide produced by mitochondrial complex III plays a pivotal role in the execution of ferroptosis induced by cysteine starvation | Litcius