Co-infusion of CAR T cells with aAPCs expressing chemokines and costimulatory ligands enhances the anti-tumor efficacy in mice
Jing Li, Weilin Zhou, Dan Li, Yong Huang, Xiao Yang, Lin Jiang, Xiaoyi Hu, Jinrong Yang, Maorong Fu, Mengxi Zhang, Fengling Wang, Jiaqian Li, Yalan Zhang, Yuening Yang, Feiyang Yan, Haozhan Gao, Wei Wang
Topics & Concepts
Chimeric antigen receptorCD80Cancer researchCCL19ChemokineImmunotherapyT cellImmunologyAntigen-presenting cellImmune systemBiologyChemistryCytotoxic T cellCD40Chemokine receptorIn vitroBiochemistryCAR-T cell therapy researchVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects