Jiedu Sangen decoction inhibits chemoresistance to 5-fluorouracil of colorectal cancer cells by suppressing glycolysis via PI3K/AKT/HIF-1α signaling pathway
Leitao Sun, Le-Yin Zhang, Feiyu Shan, Minhe Shen, Shanming Ruan
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayCancer researchAnaerobic glycolysisColorectal cancerGLUT1Cancer cellBiologyGlucose transporterApoptosisMolecular biologyChemistryPharmacologyCancerBiochemistryEndocrinologyGeneticsInsulinCancer, Hypoxia, and MetabolismColorectal Cancer Treatments and StudiesCancer, Lipids, and Metabolism