Litcius/Paper detail

Directed evolution of adeno-associated virus for efficient gene delivery to microglia

Rui Lin, Youtong Zhou, Ting Yan, Ruiyu Wang, Heng Li, Zhaofa Wu, Xinshuang Zhang, Xiangyu Zhou, Fei Zhao, Li Zhang, Yulong Li, Minmin Luo

2022Nature Methods157 citationsDOI

Topics & Concepts

MicrogliaAdeno-associated virusBiologyTransgeneGene deliveryImmune systemTransduction (biophysics)Cell biologyNeuroscienceGenetic enhancementGeneImmunologyGeneticsInflammationVector (molecular biology)Recombinant DNABiochemistryNeuroinflammation and Neurodegeneration Mechanismsinterferon and immune responsesImmune Response and Inflammation