Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations
Alicia R. Martin, Christopher R. Gignoux, Raymond K. Walters, Genevieve L. Wojcik, Benjamin M. Neale, Simon Gravel, Mark J. Daly, Carlos D. Bustamante, Eimear E. Kenny
Topics & Concepts
Genome-wide association studyLinkage disequilibriumGenetic associationPopulationGenetic architectureDemographic historyCoalescent theoryGenomicsBiologyEvolutionary biologyGeneticsQuantitative trait locusDemographyAlleleGenetic variationGenomeSingle-nucleotide polymorphismHaplotypeGenePhylogenetic treeSociologyGenotypeGenetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock