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Effects of enzymatic hydrolysis on the allergenicity of natural cow milk based on a BALB/c mouse model

Xiaona Liang, Jing Sun, Hui Yang, Jiao Cheng, Xinyang Shi, Mei Yang, Lingfen Xu, Zongzhou Wang, Yan Zheng, Xiqing Yue

2021Journal of Dairy Science12 citationsDOIOpen Access PDF

Abstract

Tregs (AT, 8.86%; PT, 9.21%; FT, 9.16%) increased significantly. Our findings indicate that exposure to HM was sufficient to induce a shift toward a Th1 response, thereby reducing potential allergenicity. Importantly, these results will lay a theoretical foundation for the development of hypoallergenic CM products.

Topics & Concepts

HistamineImmunoglobulin EAdjuvantChemistryMilk allergyFood allergySalineAllergyBALB/cImmunologyCholera toxinLactalbuminAntibodyBiologyBiochemistryEndocrinologyImmune systemFood Allergy and Anaphylaxis ResearchAllergic Rhinitis and SensitizationMast cells and histamine
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