p16High senescence restricts cellular plasticity during somatic cell reprogramming
Bogdan B. Grigorash, Dominic van Essen, Guixian Liang, Laurent Grosse, Alexander Emelyanov, Zhixin Kang, Alexey Korablev, Benoı̂t Kanzler, Clément Molina, Elsa Mallor López, Oleg N. Demidov, Carmen Garrido, Feng Liu, Simona Saccani, Dmitry V. Bulavin
Topics & Concepts
TotipotentReprogrammingCell biologySomatic cellBiologyEmbryonic stem cellSenescenceEpigeneticsStem cellCellCellular differentiationGeneticsGenePluripotent Stem Cells ResearchCRISPR and Genetic EngineeringTelomeres, Telomerase, and Senescence