Glenzocimab does not impact glycoprotein VI-dependent inflammatory hemostasis
Soumaya Jadoui, Ophélie Le Chapelain, Véronique Ollivier, Ali Mostefa-Kara, Lucas Di Meglio, Sébastien Dupont, Angèle Gros, Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Mikaël Mazighi, Bernhard Nieswandt, Stéphane Loyau, Martine Jandrot‐Perrus, Pierre H Mangin, Benoît Ho‐Tin‐Noé
Abstract
tissue-type plasminogen activator remains to ascertain, but the absence of effect of ACT017 on platelet recruitment to the inflamed vasculature suggests there is a realistic chance for it to be maintained.
Topics & Concepts
HemostasisGlycoproteinChemistryMedicineImmunologyInternal medicineBiochemistryPlatelet Disorders and TreatmentsCell Adhesion Molecules ResearchProtease and Inhibitor Mechanisms