Low-dose ketamine inhibits neuronal apoptosis and neuroinflammation in PC12 cells via α7nAChR mediated TLR4/MAPK/NF-κB signaling pathway
Jinghua Zhao, Ruxin Zhang, Wei Wang, Sheng Jiang, Huimei Liang, Guo Chen, Jingyi Qi, Huan Zeng, Houhui Song
Topics & Concepts
NeuroinflammationTLR4MAPK/ERK pathwayPharmacologyApoptosisTumor necrosis factor alphaNF-κBSignal transductionLipopolysaccharideInflammationChemistryMedicineCell biologyBiologyImmunologyBiochemistryNicotinic Acetylcholine Receptors StudyNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders