Programmable regulation of translation by harnessing the CRISPR-Cas13 system
Roser Montagud‐Martínez, Rosa Márquez‐Costa, Guillermo Rodrigo
Abstract
Development of a novel framework to regulate translation by repurposing the CRISPR-Cas13 immune system, exploiting a cell-free expression system for prototyping.
Topics & Concepts
RepurposingCRISPRTranslation (biology)Translation systemRapid prototypingComputer scienceImmune systemComputational biologyNanotechnologyChemistryEngineeringBiologyMessenger RNAMaterials scienceImmunologyBiochemistryMechanical engineeringGeneIn vitroWaste managementCRISPR and Genetic EngineeringRNA and protein synthesis mechanismsViral Infections and Immunology Research