Sculpting the dendritic landscape: Actin, microtubules, and the art of arborization
Vasileios R. Ouzounidis, Bram Prevo, Dhanya K. Cheerambathur
Abstract
Dendrites are intricately designed neuronal compartments that play a vital role in the gathering and processing of sensory or synaptic inputs. Their diverse and elaborate structures are distinct features of neuronal organization and function. Central to the generation of these dendritic arbors is the neuronal cytoskeleton. In this review, we delve into the current progress toward our understanding of how dendrite arbors are generated and maintained, focusing on the role of the actin and microtubule cytoskeleton.
Topics & Concepts
BiologyMicrotubuleNeuroscienceDendrite (mathematics)CytoskeletonActinActin cytoskeletonSensory systemFunction (biology)Cell biologyCellGeneticsMathematicsGeometryMicrotubule and mitosis dynamicsCellular Mechanics and InteractionsAdvanced Fluorescence Microscopy Techniques