Involvement of PINK1/Parkin-mediated mitophagy in mitochondrial functional disruption under oxidative stress in vitrified porcine oocytes
Jiehuan Xu, Lingwei Sun, Caifeng Wu, Shushan Zhang, Shiqiang Ju, Rong Rui, Defu Zhang, Jianjun Dai
Topics & Concepts
MitophagyParkinPINK1Oxidative stressMitochondrionReactive oxygen speciesCell biologyMFN2BiologyChemistryApoptosisBiochemistryMitochondrial DNAmitochondrial fusionInternal medicineAutophagyMedicineDiseaseParkinson's diseaseGeneAutophagy in Disease and TherapyReproductive Biology and FertilityGenetics, Aging, and Longevity in Model Organisms