PACS2 initiates foam cell formation in macrophages through the ROS-PPARγ-CD36 positive feedback loop
Jie Ouyang, Shuhua Chen, Hong Xiang, Bo Tang, Haijiao Long, Quanjun Liu, Shiying Qin, Xinru Zheng, Alex F. Chen, Hongwei Lü
Topics & Concepts
CD36Foam cellCell biologyMacrophageLipid metabolismEndoplasmic reticulumPerilipinBiologyChemistryEndocrinologyReceptorBiochemistryIn vitroAdipose tissueLipolysisCaveolin-1 and cellular processesProtein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases