Antineoplastic Mitoxantrone Monitor: A Sandwiched Mixed Matrix Membrane (MMM) Based on a Luminescent MOF–Hydrogel Hybrid
Xiao Lian, Yu Zhang, Jinmin Wang, Bing Yan
Abstract
A sandwiched mixed matrix membrane (MMM) based on a metal-organic framework-hydrogel hybrid exhibits eximious performance in the detection of mitoxantrone. Parts per billion-level sensitivity and good selectivity in serum among other analogous antineoplastics have been achieved. This flexible MMM can be used for point-of-care testing drugs in a biological medium.
Topics & Concepts
ChemistryMitoxantroneMembraneMatrix (chemical analysis)SelectivityMetal-organic frameworkLuminescenceChemical engineeringNanotechnologyOptoelectronicsChromatographyOrganic chemistrySurgeryBiochemistryChemotherapyCatalysisMaterials scienceAdsorptionPhysicsEngineeringMedicineMetal-Organic Frameworks: Synthesis and ApplicationsLuminescence and Fluorescent MaterialsCovalent Organic Framework Applications