Discovery of a novel pyroptosis inhibitor acting though modulating glutathionylation to suppress NLRP3-related signal pathway
Nenghua Zhou, Yun Zhang, Jiao Yan, Jinshan Nan, Anjie Xia, Bo Mu, Guifeng Lin, Xun Li, Shanshan Zhang, Shengyong Yang, Linli Li, Linli Li
Topics & Concepts
PyroptosisInflammasomeProinflammatory cytokineCaspase 1Cell biologyRegulatorProgrammed cell deathChemistryPharmacologyBiologyInflammationApoptosisBiochemistryImmunologyGeneInflammasome and immune disordersGout, Hyperuricemia, Uric AcidHeme Oxygenase-1 and Carbon Monoxide