Dendritic polymer-functionalized nanomedicine potentiates immunotherapy via lethal energy crisis-induced PD-L1 degradation
Xiaoling Li, Zhenyu Duan, Zhiqian Li, Lei Gu, Yinggang Li, Qiyong Gong, Zhongwei Gu, Kui Luo
Topics & Concepts
NanomedicineImmunotherapyCancer immunotherapyCancer researchPD-L1Cytotoxic T cellImmune checkpointImmune systemCancer cellCancerImmunogenic cell deathMaterials scienceMedicinePharmacologyImmunologyChemistryIn vitroNanotechnologyInternal medicineBiochemistryNanoparticleCancer Immunotherapy and BiomarkersAutophagy in Disease and TherapyImmune cells in cancer