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Slow advancement of enteral feed volumes to prevent necrotising enterocolitis in very low birth weight infants

Sam Oddie, Lauren Young, William McGuire

2021Cochrane Database of Systematic Reviews104 citationsDOIOpen Access PDF

Abstract

Early enteral feeding practices are potentially modifiable risk factors for necrotising enterocolitis (NEC) in very preterm or very low birth weight (VLBW) infants. Observational studies suggest that conservative feeding regimens, including slowly advancing enteral feed volumes, reduce the risk of NEC. However, it is unclear whether slow feed advancement may delay establishment of full enteral feeding, and if it could be associated with infectious morbidities secondary to prolonged exposure to parenteral nutrition.

Topics & Concepts

MedicineEnteral administrationObservational studyParenteral nutritionPediatricsNecrotizing enterocolitisLow birth weightRelative riskRandomized controlled trialBirth weightIntensive care medicinePregnancyConfidence intervalInternal medicineGeneticsBiologyInfant Nutrition and HealthNeonatal Respiratory Health ResearchCongenital Anomalies and Fetal Surgery
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