Systemic Inflammation after Aneurysmal Subarachnoid Hemorrhage
Chang-Zhang Chai, Ue‐Cheung Ho, Lu‐Ting Kuo
Abstract
Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological disorders, with a high mortality rate and severe disabling functional sequelae. Systemic inflammation following hemorrhagic stroke may play an important role in mediating intracranial and extracranial tissue damage. Previous studies showed that various systemic inflammatory biomarkers might be useful in predicting clinical outcomes. Anti-inflammatory treatment might be a promising therapeutic approach for improving the prognosis of patients with aSAH. This review summarizes the complicated interactions between the nervous system and the immune system.
Topics & Concepts
MedicineSubarachnoid hemorrhageInflammationSystemic inflammationStroke (engine)Immune systemIntensive care medicineBioinformaticsInternal medicineImmunologyMechanical engineeringBiologyEngineeringNeuroinflammation and Neurodegeneration MechanismsIntracranial Aneurysms: Treatment and ComplicationsIntracerebral and Subarachnoid Hemorrhage Research