MicroRNA-135 inhibits initiation of epithelial-mesenchymal transition in breast cancer by targeting ZNF217 and promoting m6A modification of NANOG
Liming Xu, Jiao Zhang, Yue Ma, Yajing Yuan, Hao Yu, Jun Wang, Xuchen Cao, Li Zhu, Ping Wang
Topics & Concepts
Gene silencingHomeobox protein NANOGBiologymicroRNADownregulation and upregulationCancer researchImmunoprecipitationChromatin immunoprecipitationMolecular biologyCarcinogenesisGene expressionCancerCell cultureGenePromoterBiochemistryEmbryonic stem cellGeneticsInduced pluripotent stem cellRNA modifications and cancerCancer-related molecular mechanisms researchMicroRNA in disease regulation