An organoid-based screen for epigenetic inhibitors that stimulate antigen presentation and potentiate T-cell-mediated cytotoxicity
Zhuolong Zhou, Kevin Van der Jeught, Yuanzhang Fang, Tao Yu, Yujing Li, Zheng Ao, Sheng Liu, Lu Zhang, Yang Yang, Haniyeh Eyvani, Mary L. Cox, Xiyu Wang, Xiaoming He, Guang Ji, Bryan P. Schneider, Feng Guo, Jun Wan, Xinna Zhang, Xiongbin Lu
Topics & Concepts
OrganoidCytotoxic T cellAntigen presentationCytotoxicityCancer researchBiologyEpigeneticsAntigenBreast cancerImmunologyImmunosurveillanceT cellImmune systemCancerCell biologyIn vitroGeneticsGeneBiochemistryEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchCancer Cells and Metastasis