Litcius/Paper detail

Integrating Bulk and Single-cell RNA-seq to Construct a Macrophage-related Prognostic Model for Prognostic Stratification in Triple-negative Breast Cancer

Hongmeng Zhao, Xuejie Zhou, Guixin Wang, Yue Yu, Yingxi Li, Zhaohui Chen, Wenbin Song, Liwei Zhao, Wang Li, Xin Wang, X B Cao, Yao Tian

2024Journal of Cancer11 citationsDOIOpen Access PDF

Abstract

Our study provides a valuable source for clarifying macrophage heterogeneity in TNBC, and a promising tool for prognostic risk stratification of TNBC.

Topics & Concepts

Breast cancerConstruct (python library)Triple-negative breast cancerRNA-SeqStratification (seeds)Risk stratificationComputational biologyMedicineOncologyMacrophageCancer researchInternal medicineCancerBiologyGene expressionGeneComputer scienceTranscriptomeGeneticsComputer networkSeed dormancyBotanyIn vitroDormancyGerminationSingle-cell and spatial transcriptomicsEsophageal Cancer Research and TreatmentFerroptosis and cancer prognosis