Design and development of efficient synthetic strategies for the chiral synthesis of novel ketolide antibiotic, nafithromycin (WCK 4873)
Satish Bhavsar, Ravikumar Tadiparthi, Sunil Gupta, Shivaji Pawar, Ravindra Yeole, Abhijeet K. Kayastha, Prasad Deshpande, Sachin Bhagwat, Mahesh Patel
Topics & Concepts
KetolideDiastereomerChiral auxiliaryChemistryStereochemistryMandelic acidCombinatorial chemistryEnantioselective synthesisAntibacterial agentOrganic chemistryAntibioticsCatalysisBiochemistryPneumonia and Respiratory InfectionsAnalytical Chemistry and ChromatographyCancer therapeutics and mechanisms