Enhancement of metabolic flux toward ε-poly-l-lysine biosynthesis by targeted inactivation of concomitant polyene macrolide biosynthesis in Streptomyces albulus
Kazuya Yamanaka, Yoshimitsu Hamano, Tadao Oikawa
Topics & Concepts
PolyeneBiosynthesisLysineChemistryStreptomycesFlux (metallurgy)BiochemistryMicrobiologyStereochemistryBiologyEnzymeAmino acidBacteriaOrganic chemistryGeneticsBiopolymer Synthesis and ApplicationsPolyamine Metabolism and ApplicationsChemical Synthesis and Analysis