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Comparing organic and metallo-organic hydrazone molecular cages as potential carriers for doxorubicin delivery

Giovanni Montà-González, David Bastante-Rodríguez, Alba García‐Fernández, Paul J. Lusby, Ramón Martínez‐Máñez, Vicente Martí‐Centelles

2024Chemical Science18 citationsDOIOpen Access PDF

Abstract

A comparative study between a metallo-organic cage and a fully organic analogous system shows that the fully organic molecular cage has a suitable stability and doxorubicin affinity for in vitro anticancer drug delivery.

Topics & Concepts

HydrazoneChemistryDoxorubicinCombinatorial chemistryOrganic chemistryMedicineSurgeryChemotherapySupramolecular Chemistry and ComplexesMetal-Organic Frameworks: Synthesis and ApplicationsMagnetism in coordination complexes
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