Confined semiconducting polymers with boosted NIR light-triggered H<sub>2</sub>O<sub>2</sub> production for hypoxia-tolerant persistent photodynamic therapy
Feng Lu, Lili Li, Meng Zhang, Chengwu Yu, Yonghui Pan, Fang-Fang Cheng, Wenbo Hu, Xiaomei Lü, Qi Wang, Quli Fan
Abstract
to produce ˙OH continuously after the termination of laser irradiation. Thus, semiconducting polymer-based nanocomposites enables NIR-II fluorescence imaging guided persistent PDT under hypoxic conditions. This work provides a promising paradigm to fabricate persistent photodynamic therapy platforms for hypoxia-tolerant phototheranostics.
Topics & Concepts
Photodynamic therapyPolymerIonMesoporous materialExcited stateFerrousMaterials scienceMesoporous silicaPhotochemistryOptoelectronicsChemistryCatalysisOrganic chemistryMetallurgyComposite materialNuclear physicsPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced Nanomaterials in Catalysis