Mechanisms of bone blood flow regulation in humans
Adina E. Draghici, J. Andrew Taylor
Abstract
The current study is the first one to noninvasively investigate control of bone blood perfusion in vivo in humans, on a moment-by-moment basis. Our results indicate that tibial bone vasculature demonstrates active vasoconstriction in response to sympathoexcitatory stimuli in young healthy individuals. Compared with whole leg vasculature, bone vasoconstrictor response seems to be smaller, delayed, and more variable.
Topics & Concepts
VasoconstrictionBlood flowIsometric exercisePerfusionMedicineHemodynamicsBone remodelingInternal medicineTibiaBlood pressureVasodilationEndocrinologyAnatomyAnesthesiaHeart Rate Variability and Autonomic ControlCardiovascular and exercise physiologyNon-Invasive Vital Sign Monitoring