Synergistic photothermal and photodynamic therapy to promote bacteria-infected wound healing using ZnO@PDA/Ag-integrated waterborne polyurethane films
Negar Salehi, Abbas Mohammadi, Vajihe Alinezhad, Shayesteh Bochani, Ali Kalantari‐Hesari, Fakhri Haghi, Francisco J. Sierra Valdez, Tomás Jafed Buenfil-Chi, Aziz Maleki, Saeed Beigi-Boroujeni
Abstract
studies in a rat wound model demonstrated accelerated wound healing and tissue regeneration with the application of ZnO@PDA/Ag in WPU nanocomposite film, particularly under NIR light irradiation. Histological analysis confirmed the formation of mature epithelial layers and minimal inflammatory response, indicating the potential of this film for clinical wound management.
Topics & Concepts
Photothermal therapyPolyurethaneMaterials sciencePhotodynamic therapyWound healingZincNanotechnologyComposite materialMedicineChemistryImmunologyMetallurgyOrganic chemistryPolydiacetylene-based materials and applicationsNanoplatforms for cancer theranostics