Construction of a layer-by-layer self-assembled rosemarinic acid delivery system on the surface of CFRPEEK implants for enhanced anti-inflammatory and osseointegration activities
Shanshan Zhao, Xingyu Zhou, Junbo Dang, Yilong Wang, Junhui Jiang, Tianhao Zhao, Dahui Sun, Chen Chen, Xin Dai, Yan Liu, Mei Zhang
Abstract
@RA group increases by 1.36 times, and the maximum pushing force increases by 2.67 times. In summary, this study provides a promising LBL based RA delivery system for the development of a dual-functional CFRPEEK implant in the field of bone implant biomaterials.
Topics & Concepts
OsseointegrationLayer (electronics)Materials scienceLayer by layerNanotechnologyDelivery systemAir layerSurface layerBiomedical engineeringImplantEngineeringMedicineSurgeryBone Tissue Engineering MaterialsBone Metabolism and DiseasesBone and Dental Protein Studies