Human Exposure to Hantaviruses Associated with Rodents of the <i>Murinae</i> Subfamily, Madagascar
Harinirina Aina Rabemananjara, Vololoniaina Raharinosy, Ravo M. Razafimahefa, Jean Pierre Ravalohery, Jean Théophile Rafisandratantsoa, Soa Fy Andriamandimby, Minoarisoa Rajerison, Soanandrasana Rahelinirina, Aina Harimanana, Judickaëlle Irinantenaina, Marie‐Marie Olive, Christophe Rogier, Noël Tordo, Rainer G. Ulrich, Jean‐Marc Reynes, Stéphane Pêtres, Jean‐Michel Héraud, Sandra Telfer, Claudia Filippone
Abstract
We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2%; 10/139).
Topics & Concepts
SeroprevalenceHantavirusHantavirus InfectionSerologyVirologyBiologySubfamilyRodentArvicolinaePuumala virusHantavirus pulmonary syndromeZoologyVirusAntibodyImmunologyEcologyGeneticsGeneMicrotusViral Infections and VectorsFire effects on ecosystemsViral Infections and Outbreaks Research