Anticancer evaluation of new organometallic ruthenium(<scp>ii</scp>) flavone complexes
Mai A. Khater, John A. Brazier, Francesca Greco, Helen M. I. Osborn
Abstract
< 0.05) particularly on the MDA-MB-231 cell line. The test derivatives also showed non-intercalative interaction with VEGF and c-myc i-motif DNA sequences.
Topics & Concepts
ChemistryFlavonesRutheniumAngiogenesisIn vitroMetastasisCancer researchSmall moleculeCell cultureCytotoxicityCell growthPharmacologyBiochemistryStereochemistryCancerBiologyInternal medicineCatalysisMedicineChromatographyGeneticsMetal complexes synthesis and propertiesSynthesis and biological activityFerrocene Chemistry and Applications