Tetracycline Resistance Mediated by <i>tet</i> (M) Has Variable Integrative Conjugative Element Composition in Mycoplasma hominis Strains Isolated in the United Kingdom from 2005 to 2015
Victoria J. Chalker, Martin Sharratt, Christopher L. Rees, Oliver H. Bell, Edward Portal, Kirsty Sands, Matthew S. Payne, Lucy C. Jones, O. Brad Spiller
Abstract
A minimal genome and absent bacterial cell wall render Mycoplasma hominis inherently resistant to most antimicrobials except lincosamides, tetracyclines, and fluoroquinolones. Often dismissed as a commensal (except where linked to preterm birth), it causes septic arthritis in immunodeficient patients and is increasingly associated with transplant failure (particularly lung) accompanying immunosuppression.
Topics & Concepts
TetracyclineMycoplasma hominisMicrobiologyBiologyMycoplasmaAntibioticsMicrobial infections and disease researchBlood groups and transfusionRabies epidemiology and control