The Mpro structure-based modifications of ebselen derivatives for improved antiviral activity against SARS-CoV-2 virus
Zhen Qiao, Ningning Wei, Lin Jin, Hongyi Zhang, Jiajie Luo, Yanru Zhang, KeWei Wang
Topics & Concepts
EbselenChemistryViral replicationProteaseIC50BiochemistryPharmacologyStereochemistryEnzymeVirusIn vitroVirologyGlutathioneBiologyGlutathione peroxidaseComputational Drug Discovery MethodsSynthesis and biological activityResearch on Leishmaniasis Studies